New strategy for discovery of enzyme inhibitors: Screening with intact mammalian cells or intact microorganisms having special functions.
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چکیده
منابع مشابه
Enzyme immunoassay for intact human insulin in serum or plasma.
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9-substituted adenine derivatives with protected phosphoryl groups were synthesized and tested as inhibitors of adenylyl cyclase in isolated enzyme and intact cell systems. Protected 3'-phosphoryl derivatives of 2',5'-dideoxyadenosine (2',5'-dd-Ado) and beta-l-2',5'-dd-Ado, protected 5'-phosphoryl derivatives of beta-l-2',3'-dd-Ado, and protected phosphoryl derivatives of two 9-(2-phosphonometh...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1990
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.43.1207